EPA Reevaluation of Dioxin's Risks
نویسندگان
چکیده
The importance of axillary dissection as part of the primary surgical procedure in the treatment of operable cases of carcinoma of the breast is established. The morbidity of this procedure, however, is less well documented. A study of 126 women who had had full axillary dissection as part of their initial surgical treatment was undertaken to assess their degree of morbidity in terms of numbness, pain, weakness, swelling, and stiffness. Seventy per cent of cases complained of numbness, 33% of pain, 25% of weakness, 24% of limb swelling, and 15% of stiffness. Objective measurements confirmed decreased sensation in 81%, weakness in 27%, swelling in 10%, and stiffness in 10%. In no case were these symptoms described as severe, though they did have an effect upon the daily lives of 39%. The side effects of full axillary dissection are common and all women should be warned of them prior to surgery; however they are usually mild and therefore should not preclude this procedure as a part of definitive surgical treatment.
منابع مشابه
Receptor mechanisms and dose-response models for the effects of dioxins.
There is increasing evidence that receptor-mediated events impact one or more stages responsible for tumor development in experimental animals and humans. Although many chemicals and endogenous hormones require receptor interactions as a necessary event in their carcinogenic activity, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and its structural analogs are the most visible examples of receptor...
متن کاملA Life Stage Approach to Assessing Children’s Exposures
Background Considering risks to infants and children as part of risk assessments are of primary importance to the U.S. Environmental Protection Agency (EPA). In 1995, EPA issued a policy for “Evaluating Health Risks to Children” (U.S. EPA, 1995), to ensure that risks to infants and children are consistently and explicitly a part of risk assessments conducted in support of the decision making pr...
متن کاملTen Years of Addressing Children’s Health through Regulatory Policy at the U.S. Environmental Protection Agency
BACKGROUND Executive Order (EO) 13045, Protection of Children From Environmental Health Risks and Safety Risks, directs each federal agency to ensure that its policies, programs, activities, and standards address disproportionate environmental health and safety risks to children. OBJECTIVES We reviewed regulatory actions published by U.S. Environmental Protection Agency (EPA) in the Federal R...
متن کاملDispersion and Health Risk Assessment of PM10 Emitted from the Stacks of a Ceramic and Tile industry in Ardakan, Yazd, Iran, Using the AERMOD Model
Background: In developing countries, air pollution caused by industries constitutes a serious threat to public health. The present study was conducted to determine the dispersion patern and assess the health risks of PM10 emitted from the stacks of a ceramic and tile factory. Materials and Methods: The present descriptive-cross sectional study was performed on a tile and ceramic industry in Ard...
متن کاملRenewing the Federal Commitment to Advance Children’s Health: The President’s Task Force on Environmental Health Risks and Safety Risks to Children
Eighteen years ago President William Clinton issued Executive Order 13045 calling for each federal agency to “ensure that its policies, programs, activities, and standards address disproportionate risks to children that result from environmental health risks or safety risks” (Clinton and Gore 1997). As part of this Executive Order, Clinton established the President’s Task Force on Environmental...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Environmental Health Perspectives
دوره 101 شماره
صفحات -
تاریخ انتشار 1993